Stem cell-derived photoreceptors: Do they have the right stuff?

david gammDavid M. Gamm, MD, PhD

RRF Emmett Director of McPherson Eye Research Institute

Sandra Lemke Trout Chair in Eye Research

Professor of Ophthalmology and Visual Sciences, University of Wisconsin-Madison

“Stem cell-derived photoreceptors: Do they have the right stuff?”

October 26th,12:00 – 1:00 pm

R2-265, Academic Research Building

Functional replacement of degenerated photoreceptors and other neuronal cell types has been a lofty goal of human pluripotent stem cell technology since its inception. But how do hPSC-derived photoreceptors stack up against the “real thing”, and do they retain enough plasticity to reach out and make new connections when called upon to do so? I will present studies examining three critical, intrinsic properties of donor photoreceptors – light responsivity, axonal outgrowth, and synaptic plasticity – in order to gauge their readiness for use in clinical trials

While the seminar will be in person, a Zoom link is also available:

Join Zoom Meeting

Meeting ID: 972 1908 9656Passcode: 063033